ABC6 ORGANISERS:


 


 

SPONSORS:

 ABC6 SECRETARIAT:

     Publicon PCO
     +372 740 4095
     abc6@publicon.ee

 

ABC6 
Autoimmunity: Basic and Clinical   
Programme

Tartu, Estonia, May 27-29, 2019 

 

We would like to draw your attention to the fact that the event is not subjected to a fee. However, registration for the conference is necessary. The latest date for registration is 1 May, 2019. The registration form is available here.

 

DAY 1: May 27, 2019 

Day of Arrival

 

DAY 2: May 28, 2019

08:30 - 09:00 Registration
09:00 - 09:20

WELCOME NOTE

Raivo Uibo (University of Tartu, Estonia)
Welcome note 

Anders Örn (Karolinska Institute, Sweden)
Historical retrospective

09:20 - 10:50

SESSION 1

  Chair: Reinhold Schmidt (Hannover Medical School, Germany)

09:20 - 10:05 (45:00) 

Seppo Meri (University of Helsinki, Finland)
How does complement-mediated inflammation creep into our blood vessels to cause damage in heart, kidneys and brain?

10:05 - 10:50 (45:00)

Petter Brodin (Karolinska Institute, Sweden)
Human immune variation

10:50 - 11:20 Refreshment break (30 min)
11:20 - 12:50 

SESSION 2

  Chair: Seppo Meri (University of Helsinki, Finland)

11:20 - 12:05 (45:00)

Tadej Avcin (Ljubljana University Medical Centre, Slovenia)
Autoimmunity in PID and implications for targeted therapeutics

12:05  - 12:50 (45:00)

Reinhold Schmidt (Hannover Medical School, Germany)
The new paradigm: the interrelationship between autoimmunity and immunodeficiency

12:50 - 13:50 Lunch (60 min)
13:50 - 14:30 Panel Discussion (40 min)



Chair: Seppo Meri (University of Helsinki, Finland)
What are the causes of autoimmunity?
14:30 - 16:00

SESSION 3

  Chair: Kai Kisand (University of Tartu)

14:30 - 15:15 (45:00)

Vivianne Malmström (Karolinska Institute, Sweden)
Autoantigens and autoreactive lymphocytes in rheumatoid arthritis

15:15 - 16:00 (45:00)

Annamari Ranki (University of Helsinki, Finland)
From clinical symptoms to the identification of specific pathways and targeted therapy

16:00 - 17:00

Poster Session (with coffee, snacks and beverages)

 

DAY 3: May 29, 2019

09:00 - 11:15

SESSION 4

  Chair: Pärt Peterson (University of Tartu)

09:00 - 09:45 (45:00) 

Dmitriy Chudakov (Institute of Bioorganic Chemistry, Russian Federation)
Identification of condition-associated TCR motifs, applications in autoimmunity

09:45 - 10:30 (45:00)

Richard Oram (University of Exeter Medical School, United Kingdom)
Clinical and research uses of genetic risk scores in autoimmune disease

10:30 - 11:00 Refreshment break (30 min)
11:00 - 12:30 Selected presentations from the abstracts (10+5 min)
  Chair: Anders Örn (Karolinska Institute, Sweden)




11:00 - 11:15

Liis Haljasmägi (University of Tartu, Estonia) 
Type I IFN neutralizing autoantibodies in patients with systemic lupus erythematosus

11:15 - 11:30

Aili Tagoma (University of Tartu, Estonia) 
Peripheral blood cytokines in second trimester of pregnancy

11:30 - 11:45

Astrid Oras (University of Tartu, Estonia)
Altered peripheral blood immune cell profile in newly diagnosed young type 1 diabetes patients

11:45 - 12:00

Kadri Kangro (IRF Life Sciences, KU Leuven Campus Kulak Kortrijk, Belgium)
Fine mapping of anti-ADAMTS13 autoantibodies in immune mediated thrombotic thrombocytopenic purpura patients using a large library of ADAMTS13 domains

12:00 - 12:15

Anet Kivihall (University of Tartu, Estonia)
The expression and function of miR-146a/b in human bronchial epithelial cells

12:15 - 12:30

Epp Kaleviste (University of Tartu, Estonia)
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined

12:30 - 13:30 Lunch (60 min)
13:30 - 15:45

SESSION 5

  Chair: Raivo Uibo (University of Tartu)
13:30 - 14:15 (45:00)

Niklas Beyersdorf (Julius-Maximilians-Universität Würzburg, Germany)
CD28-mediated co-stimulation of T cells as a therapeutic target in autoimmunity

14:15 - 15:00 (45:00)

Frits Koning (Leiden University Medical Center, Netherlands)
Imaging the unimaginable with (imaging) mass cytometry  

  15:00 - 15:45 (45:00)

David Hunt (University of Edinburgh, UK)
Type I interferon: both a friend and foe in neuroinflammation?

15:45 - 16:00 Concluding remarks
16:00 - 16:30

Farewell coffee and snacks